PTSD and Cognition Published Clinical Study: Transcranial-Intranasal Photobiomodulation | Vielight Neuro
Reference: Tate, J., Lindsey, A., Wilde, L. (2025). Photobiomodulation for Cognitive Function and Wellness in Firefighters: A Pilot Study. Photobiomodulation, Photomedicine, and Laser Surgery. DOI: 10.1177/15578550251362096
This article is for educational purposes only and summarizes published clinical research on transcranial-intranasal photobiomodulation using Vielight technology in a firefighter population. The Vielight Neuro is a general wellness device. It is not intended to diagnose, treat, cure, or prevent PTSD. Consult a qualified healthcare professional for medical or mental health concerns.
Why This Study Matters
Firefighters endure extreme stress, traumatic events, and irregular schedules that can lead to:
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Poor sleep and chronic fatigue
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Persistent pain
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Mood dysregulation
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PTSD symptoms
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Cognitive decline
Traditional wellness strategies—counseling, fitness, therapy—help, but may not fully address the neurological impact of sustained stress.
Researchers at the University of Utah investigated a new, non-invasive approach: transcranial-intranasal photobiomodulation (itPBM) — delivering near-infrared light to the brain through the nose and scalp using the Vielight Neuro Gamma to promote cellular health, reduce inflammation, and support brain network function.
How the Study Worked
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Participants: 16 active-duty male firefighters (ages 25–58, mean ~43)
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Device: Vielight Neuro Alpha
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Wavelength: 810 nm near-infrared light
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Modulation: 10 Hz
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Configuration: Four transcranial LED clusters targeting default mode network hubs + one intranasal LED targeting ventral prefrontal cortex
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Schedule:
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20 minutes per session
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3–4 sessions per week
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8 weeks total (~25 sessions)
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Measurements: Standardized tests for PTSD symptoms, pain interference, mood disturbance, fluid cognition, and reintegration readiness.
Results at a Glance
| Outcome Measure | Baseline Mean (SD) | Post-Treatment Mean (SD) | p-Value | Effect Size (Cohen’s d) |
|---|---|---|---|---|
| PTSD Checklist (PCL-5) | 28.9 (12.0) | 17.4 (8.4) | 0.003 | 1.08 (large) |
| PROMIS Pain Interference | 57.0 (7.5) | 51.8 (7.4) | 0.018 | 0.72 (moderate) |
| NIH Toolbox Fluid Cognition | 102.0 (12.0) | 108.8 (11.5) | 0.009 | 0.83 (large) |
| Mood Disturbance (POMS-TMD) | 41.7 (8.2) | 36.0 (7.0) | 0.012 | 0.74 (moderate) |
| Reintegration Index | 85.2 (8.0) | 90.7 (6.7) | 0.007 | 0.84 (large) |
Compliance: Over 90% attendance rate
Adverse Effects: None reported
What This Means
The therapy led to statistically and clinically significant improvements in:
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PTSD symptom severity
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Daily life pain interference
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Problem-solving, memory, and cognitive flexibility
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Emotional stability
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Readiness for social reintegration
The effect sizes were moderate to large, meaning these improvements are likely noticeable in real-world settings.
Why It’s Exciting
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Safe & drug-free — no reported side effects
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Time-efficient — 20 minutes per session
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Portable & scalable — possible integration into fire stations, clinics, and wellness centers
While this was a small, uncontrolled pilot, it’s a strong signal that larger randomized controlled trials are warranted.
“If tPBM can improve resilience, cognition, and recovery in firefighters, its potential for other high-stress professions—like healthcare workers, police, and veterans—is enormous.”